Many microbial strains, including those found in commercial bio pesticides, have shown notable effectiveness against nematodes and soil-borne diseases over the last half-century. These microbes use a variety of tactics, including competition for resources and space, induced systemic resistance, hyperparasitism, and antibiosis, to inhibit plant diseases. Furthermore, because they fix nitrogen, solubilise phosphate, chelate iron, generate phytohormones, breakdown ACC deaminase, and break down organic debris to release nutrients into the soil, a number of microorganisms also serve as biofertilizers and encourage plant development. Ecological deterioration, toxic residues in crops, and heightened resistance among phytopathogens such as Sclerotinia, Rhizoctonia, Pythium, and others have resulted from intensive agriculture`s over-reliance on synthetic pesticides. These substances also reduce the number of helpful microorganisms that improve soil fertility by upsetting soil biodiversity. Given these difficulties, bio control agents (BCAs) seek to provide a sustainable, eco-friendly, and economical substitute for synthetic pesticides whether applied directly to the soil or as seed treatments. Plant endophyes, which are a recent development in bio control techniques, also function as BCAs.