Apr , 2020, Volume : 1 Article : 24
COVID-19: Genome Sequencing and Detection
Author : Sonam S. Kale, Kishor P. Panzade, Narendra R. Chavan
Genome sequencing and annotation of the SARS-CoV-2 (Severe Acute Respiratory Syndrome) is necessary to study their origin, evolution, mode of action, pathogenicity, and for their detection, diagnosis and production of vaccines. The genome sequencing by various countries reported that it has a genome size of 30 kb, one of the largest among RNA viruses. The coronavirus has become the major pathogen of emerging respiratory disease outbreaks seems the symptoms like pneumonia where the detection through some normal symptoms and test in humans is not possible. Thus it requires special detection techniques includes the NAAT test, serological test and medical imagining.
COVID-19 Genome sequencing and detection.pdf
Dr. Sonam Sureshrao Kale
Dear Rathod Vilas, Coronavirus mainly attacks the lungs in the beginning and probably also attacks, to a lesser degree, other organs that express ACE2, such as the kidneys and gastrointestinal system. Nevertheless, respiratory dysfunction and failure are the major threat to the patients and the major cause of death. To date, so many families of this virus have been reported that were evolved through the selection pressure and spontaneous mutation in their genome. By inducing a mutation new families of viruses may evolved.