Tocopherol is important as a potent antioxidant that helps protect cells and tissues from oxidative damage. This article provides an in-depth exploration of tocopherols, bioactive compounds found in plants, and their multifaceted roles in both plant physiology and human health. It covers the sources of tocopherols in plants, their functions in protecting against oxidative stress, and their potential health benefits for humans, including reducing the risk of chronic diseases and promoting brain health. The article also discusses extraction and analysis techniques for tocopherols and their significance in plant-based foods and nutritional supplements. Furthermore, it highlights emerging research areas, such as the use of tocopherols in cosmetics for skincare applications.